Thanks to its large seabird population, the Farallon Islands were a particularly dangerous destination during the Gold Rush. As San Francisco's population grew, eggs became expensive and scarce.

This study found that mice consume and/or compete for food with native species such as the endemic ... to eradicate mice from all of the South Farallon Islands. Disclaimer: AAAS and EurekAlert!

As reported by sfgate.com, the Farallon Islands have hosted one of just two fur seal rookeries south of Alaska since the species was completely wiped out from the area in the early 19th century.