While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...
If these DNA breaks aren't repaired, they can prompt cells to self-destruct, or failing that, become cancerous.As LIG4 syndrome impairs this response, people with the condition are particularly ...
Hosted on MSN15d
Is anti-aging science misguided? ‘Reversing’ your biological clock may be out of reachIn a nutshell Scientists discovered that random DNA mutations don’t just cause local damage, they trigger widespread changes ...
Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication. Neurons, however, do not divide. For this reason, they are at ...
A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.
Sunburn has traditionally been attributed to UV-induced DNA damage, but it turns out that this is not the full truth.
Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback