Using Foldit, a protein structure prediction software, the team designed an insect cell-derived polyhedra crystal (PhC) as a scaffold onto which the c-Myc fragments would bind. To speed up the ...
The crystal structure of a second G protein ... For comparison, the r.m.s. deviation for the kinase domains of the closely related protein kinases PKA and PKC is also ∼2.3 Å, but their ...
Mammalian AMP-activated protein kinase (AMPK) was discovered as a ... and γ-subunits with tandem domains that bind AMP or ATP. Recent crystal structures are providing insights into the ...