An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and villi in the intestine using a contact protein printing technique.

In a recently published Science paper, 1 his team described how they developed a biomaterial tissue scaffold that allows intestinal stem cells to self-organize into organoids with patterned crypt-like ...

These Lgr5+ cells were located at the very bottom of glands, or crypts, in the intestinal lining. However, in the last decade, problems with this model began to appear. Deleting the Lgr5+ cells in ...

The epithelial lining of our intestine is organized in a crypt-villi architecture and serves many essential functions including maintenance of barrier, digestion and nutrient absorption. Due to the ...

and bond formation to study how intestinal stem cell colonies respond to alterations in geometric confinement, mirroring processes observed in vivo. Looking ahead, we seek to identify unique ...