Interestingly, CTLA-4 knockout mice and mice that lack expression of CTLA-4 just in T REG develop fatal, early-onset lymphoproliferative disease. 1,4 In addition, expression and signaling of CTLA ...
Clinical-stage biopharmaceutical company OncoImmune develops first-in-class and best-in-class cancer therapeutics and is pioneering new pathways ... CD24–Siglec and CTLA-4 signaling, and a ...
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