Primary CNS lymphoma (PCNSL) is a nervous-system-seeking extranodal non-Hodgkin's lymphoma that shares common morphologic and molecular features with diffuse large B-cell lymphoma Lymphomagenesis ...
Background: Methotrexate-based chemotherapy is the first-line treatment for patients with primary central nervous system lymphoma (PCNSL); however, in most cases this disease remains incurable.