Molecules of sickle-cell hemoglobin stick to one another ... often resulting in a frameshift One form of beta-thalassemia Deletion One or more nucleotides is "skipped" during replication or ...

Because of the paucity of red blood cell precursors capable of synthesizing hemoglobin in the blood of normal people or people with thalassemia ... diversity in the structure of the α-globin ...

There were no serious adverse events or treatment-related mortalities. Evidence Rating Level: 2 (Good) Study Rundown: Transfusion-dependent β-thalassemia (TDT) is a condition that results in iron ...