Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

A revolutionary approach to immune therapy has emerged: engineered immune cells that protect healthy tissue without ...

People with prediabetes often develop diabetes, but many of them manage to reverse to normoglycemia. What determines these ...

Mitochondria are well known as the powerhouses of the cell. These crucial, energy generating organelles even have their own little genomes... | Cell And Molecular Biology ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

Researchers at IISc Bengaluru discover potential drug-free treatment for diabetes by enhancing beta-cell function with small molecules.

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...

There isn't a cure for the condition, but doctors may recommend medications to slow down the progression of the disease or ...

Beta Bionics has set the terms for its plan to go public, with a goal of raising at least $114 million to support its artificial pancreas system for people with Type 1 diabetes. The California ...

glucagon secretion is stimulated to promote endogenous glucose production in the liver…while high plasma glucose concentrations trigger insulin secretion from pancreatic beta cells, low- plasma ...