These chains are interconnected by disulfide bonds, resulting in a characteristic Y-shaped structure with a total molecular weight of approximately 150 kDa. Each antibody molecule possesses ...

These chains are held together by disulfide bonds and non-covalent interactions. The structure of an antibody can be divided into several key regions: Variable Regions (Fab): Located at the tips of ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.