People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...

I underwent an oophorectomy at MD Anderson due to my BRCA1 gene mutation ... vital for repairing cell damage and ensuring proper cell function. However, this process is disrupted when a BRCA ...

The genetic basis of Fanconi ... to genes encoding proteins of known function. The product of a sixth, newly-cloned FA-associated gene has been linked to BRCA1, and may finally offer some insight ...

Andrew Teschendorff, Professor at the Chinese Academy of Sciences, is developing computational systems-biological tools to ...

The screening programme looks for mutations in the BRCA genes which push up a person’s risk of cancer. Everyone has BRCA1 and BRCA2 genes, but people who have changes in the gene are at higher ...

A landmark study found a specific mutation of the BRCA1 gene which could have begun with a single individual in Westray hundreds of years ago. Researchers found that about one in 100 people with ...

Many people with VUS may be notified about the reclassification of their VUS as the ClinVar BRCA1/2 expert panel and testing laboratories use the new information in testing reports and updates.