The STARS-BNP trial [42] was the first large trial to demonstrate improved outcomes using a natriuretic peptide-guided approach in patients with HF. The investigators enrolled 220 participants ...

the study shows that BNP is a strong prognostic indicator in heart failure, irrespective of disease stage. Furthermore, BNP appears to be superior to established prognostic indicators, and might ...

Possible Roles for Nesiritide in the Management of Heart Failure Although the majority of heart failure patients are ambulatory, with NYHA functional class I or II symptoms, the bulk of clinical ...

BNP is a “stretch” hormone that indicates stretching or increased pressure that occurs with HF. Based on the stage of your heart failure, a doctor will work with you to create a treatment plan ...

An assay measuring N-terminal pro-BNP, or NT-proBNP, is more sensitive to detect heart failure and used in many institutions. The levels of BNP and NT-proBNP are essentially the same in normal ...

Chronic heart failure ... AHA heart failure staging in that NYHA allows movement from any one class to another while the ACC/AHA system only allows unidirectional progression of stages (A→B ...

although that's not wholly surprising in an early-stage trial in heart failure. It also missed the mark in two exploratory outcome measures – the change from baseline in NT-pro BNP – a peptide ...