World champion Federica Brignone defied poor health again to claim back-to-back giant slalom World Cup victories in her native Italy while American star Mikaela Shiffrin failed to qualify for the second run for the first time in a dozen years.

Federica Brignone made it a giant slalom double at Sestriere after storming to a second straight World Cup victory on home snow after Mikaela Shiffrin failed to even qualify for Saturday's second run.

Saturday of smiles and victories for Federica Brignone who triumphed in the Sestriere Giant Slalom, continuing to write pages of Italian skiing history and reaching 34 World Cup victories.